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Proteintech
PPP1R15B Polyclonal Antibody
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产品信息
14634-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PPP1R15B Fusion Protein Ag6213 (369-713 aa encoded by BC065280)
偶联物
形式
Liquid
浓度
0.29 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: TTEVPLALE EESPSEGCPS SEIPMEKEPG EGRISVVDYS YLEGDLPISA RPACSNKLID YILGGASSDL ETSSDPEGED WDEEAEDDGF DSDSSLSDSD LEQDPEGLHL WNSFCSVDPY NPQNFTATIQ TAARIVPEEP SDSEKDLSGK SDLENSSQSG SLPETPEHSS GEEDDWESSA DEAESLKLWN SFCNSDDPYN PLNFKAPFQT SGENEKGCRD SETPSESIVA ISECHTLLSC KVQLLGSQES ECPDSVQRDV LSGGRHTHVK RKKVTFLEEV TEYYISGDED RKGPWEEFAR DGCRFQKRIQ ETEDAIGYCL TFEHRERMFN RLQGTCFKGL NVLKQC (369-713 aa encoded by BC065280)
靶标信息
Maintains low levels of EIF2S1 phosphorylation in unstressed cells by promoting its dephosphorylation by PP1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Constitutive repressor of eIF2alpha phosphorylation; CReP; Protein phosphatase 1 regulatory subunit 15B; protein phosphatase 1, regulatory (inhibitor) subunit 15B
基因别名: 1810033K10Rik; AI606441; C530022L24Rik; CREP; MSSGM2; PPP1R15B
UniProt ID: (Human) Q5SWA1, (Mouse) Q8BFW3
Entrez Gene ID: (Human) 84919, (Rat) 304799, (Mouse) 108954
response to oxidative stress
ER overload response
dephosphorylation
response to endoplasmic reticulum stress
response to hydrogen peroxide
regulation of translation
regulation of translational initiation
peptidyl-serine dephosphorylation
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
negative regulation of protein phosphorylation
negative regulation of PERK-mediated unfolded protein response
