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Invitrogen
RACK1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-82771
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
规格
10 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: CVRFSPNSSN PIIVSCGWDK LVKVWNLANC KLKTNHIGHT GYLNTVTVSP DGSLCASGGK DGQAMLWDLN EGKHLYTLDG
Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.
靶标信息
RACK1 (receptor for activated C kinase 1) was identified through its binding to various PKC isoforms. Its main function is to recruit PKC and various other proteins to specific locations to form multiprotein complexes, mediating various signal pathways. RACK1 is required for VANGL2 membrane localization and for PTK2/FAK1 phosphorylation and dephosphorylation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 12-3; activated protein kinase C receptor; cell proliferation-inducing gene 21 protein; GNB2L1; guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 sequence 1; guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1; guanine nucleotide binding protein beta polypeptide 2-like 1; guanine nucleotide binding protein related; guanine nucleotide binding protein, beta 2, related sequence 1; guanine nucleotide-binding protein subunit beta-2-like 1; guanine nucleotide-binding protein subunit beta-like protein 12.3; human lung cancer oncogene 7 protein; lung cancer oncogene 7; OTTHUMP00000223870; OTTHUMP00000223891; OTTHUMP00000223893; OTTHUMP00000223900; OTTHUMP00000223901; OTTHUMP00000223902; OTTHUMP00000223930; OTTHUMP00000223931; PIG21; proliferation-inducing gene 21; protein homologous to chicken B complex protein, guanine nucleotide binding; rack-1; receptor of activated protein C kinase 1; receptor of activated protein kinase C 1; unnamed protein product
基因别名: GB-like; Gnb2-rs1; GNB2L1; H12.3; HLC-7; p205; PIG21
UniProt ID: (Human) P63244, (Mouse) P68040
Entrez Gene ID: (Human) 10399, (Mouse) 14694
RNA binding
protein kinase C binding
receptor binding
protein binding
enzyme activator activity
ion channel inhibitor activity
enzyme binding
protein phosphatase binding
protein serine/threonine kinase inhibitor activity
protein tyrosine kinase inhibitor activity
cyclin binding
receptor tyrosine kinase binding
signaling adaptor activity
SH2 domain binding
identical protein binding
protein homodimerization activity
ribosome binding
translation regulator activity
cadherin binding
BH3 domain binding
binding, bridging
cysteine-type endopeptidase activator activity involved in apoptotic process
signaling receptor activity
positive regulation of protein phosphorylation
translation
apoptotic process
protein localization
negative regulation of gene expression
protein ubiquitination
negative regulation of translation
negative regulation of Wnt signaling pathway
negative regulation of cell growth
positive regulation of cell migration
positive regulation of protein complex assembly
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of protein localization
tumor necrosis factor-mediated signaling pathway
intracellular signal transduction
positive regulation of Golgi to plasma membrane protein transport
positive regulation of apoptotic process
pigmentation
positive regulation of GTPase activity
negative regulation of smoothened signaling pathway
negative regulation of phagocytosis
regulation of cell division
regulation of cell cycle
negative regulation of protein kinase B signaling
positive regulation of mitochondrial depolarization
cellular response to glucose stimulus
cellular response to growth factor stimulus
rescue of stalled ribosome
regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
regulation of protein localization to plasma membrane
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
regulation of establishment of cell polarity
positive regulation of gastrulation
negative regulation of translational frameshifting
positive regulation of intrinsic apoptotic signaling pathway
cytoplasmic translation
negative regulation of protein binding
negative regulation of endoplasmic reticulum unfolded protein response
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