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Invitrogen
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: CNDLELCDEA MALLDEVIMC TFQQSVYYLT KTLYSTLPAL LDSNPFTAGA ELPGPGAELG AMPPGLRP
Highest antigen sequence indentity to the following orthologs: Mouse - 97%, Rat - 97%.
Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: RAIN; unnamed protein product
基因别名: RAIN
UniProt ID: (Human) Q5U651
Entrez Gene ID: (Human) 54922