Invitrogen

RGS19 Polyclonal Antibody

Name: RGS19 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-84831

高级验证

查看其他9个RGS19抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (2)
高级验证 (1)

RGS19 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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RGS19 Antibody (PA5-84831) in IHC (P)

Immunohistochemical analysis of RGS19 in human cerebral cortex using RGS19 Polyclonal Antibody (Product # PA5-84831) shows low expression as expected.

Product Image Gallery

RGS19 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of RGS19 demonstrates antibody specificity. Immunohistochemical analysis of RGS19 using anti-RGS19 Polyclonal Antibody (Product #PA5-84831), shows significant staining of RGS19 in lymph node and shows minimal or weak staining in cerebral cortex tissues. The relative expression levels of RGS19 within each tissue is shown using RNA-Seq. {RE}

Immunogen image

Immunogen Image RGS19 Polyclonal Antibody

产品信息

PA5-84831

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:1,000-1:2,500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human RGS19. Recombinant protein control fragment (Product #RP-108247).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2791980

产品详细信息

Immunogen sequence: QPLPSCEVCA TPSPEEVQSW AQSFDKL

Highest antigen sequence indentity to the following orthologs: Rat - 93%, Mouse - 89%.

靶标信息

RGS19 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, predominantly to G(i)-alpha-3. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: G alpha interacting protein; G protein signalling regulator 19; G-alpha-interacting protein; GAIP; GAIP protein; GS19; guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein; Regulator of G-protein signaling 19; regulator of G-protein signalling 19; RGS19

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基因别名: GAIP; GNAI3IP; RGS19; RGSGAIP

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UniProt ID: (Human) P49795

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Entrez Gene ID: (Human) 10287

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功能

G-protein alpha-subunit binding GTPase activator activity protein binding beta-catenin binding protein kinase binding armadillo repeat domain binding GTPase-activating protein

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