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Proteintech
RRM1 Polyclonal Antibody
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产品信息
10526-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
已发表种属
Human,
Xenopus
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RRM1 Fusion Protein Ag0789 (593-792 aa encoded by BC006498)
偶联物
形式
Liquid
浓度
0.22 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: IRNSLLIAP MPTASTAQIL GNNESIEPYT SNIYTRRVLS GEFQIVNPHL LKDLTERGLW HEEMKNQIIA CNGSIQSIPE IPDDLKQLYK TVWEISQKTV LKMAAERGAF IDQSQSLNIH IAEPNYGKLT SMHFYGWKQG LKTGMYYLRT RPAANPIQFT LNKEKLKDKE KVSKEEEEKE RNTAAMVCSL ENRDECLMCG S (593-792 aa encoded by BC006498)
靶标信息
RRM1 (Ribonucleotide reductase M1 polypeptide) is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme which catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RRM1 is involved in carcinogenesis, tumor progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: R RRM 1; RI RI RR 1; Ribonucleoside-diphosphate reductase large subunit; Ribonucleoside-diphosphate reductase subunit M1; Ribonucleotide reductase large subunit; ribonucleotide reductase M1 polypeptide; ribonucleotide reductase, R1 subunit; RIR 1
基因别名: R1; RIR1; RnrM1; RR1; RRM1
UniProt ID: (Human) P23921, (Mouse) P07742
Entrez Gene ID: (Human) 6240, (Rat) 685579, (Mouse) 20133
mitotic cell cycle
pyrimidine nucleobase metabolic process
DNA replication
male gonad development
deoxyribonucleotide biosynthetic process
response to ionizing radiation
nucleobase-containing small molecule interconversion
cell proliferation in forebrain
protein heterotetramerization
oxidation-reduction process
retina development in camera-type eye
protein oligomerization
metabolic process
