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Bioss

Rab3A+Rab3B+Rab3C+Rab3D Polyclonal Antibody

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说明书
Certificates
实验方案
问题与答案
技术支持
说明书
Certificates
实验方案
问题与答案
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产品信息

BS-6180R

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:300
-

免疫组化（石蜡） (IHC (P))

1:400
-

免疫组化（冰冻） (IHC (F))

1:100-1:500
-

免疫细胞化学 (ICC/IF)

1:50-1:200
-

酶联免疫吸附实验 (ELISA)

1:500-1:1,000
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide derived from human Rab3A+Rab3B+Rab3C+Rab3D.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

规格

100 µg

纯化类型

Protein A

保存液

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

内含物

0.02% ProClin 300

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has four known isoforms: 3A, 3B, 3C and 3D. These proteins are expressed in the highest concentration in the brain and endocrine tissues and are involved in regulated exocytosis of hormones and neurotransmitters. Specifically Rab3's are thought to play a role in presynaptic vesicle trafficking and priming.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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Cite this product

生物信息学

蛋白别名: brain antigen RAB3B; epididymis secretory sperm binding protein; glioblastoma overexpressed; Rab3D upregulated with myeloid differentiation; RAS-associated protein RAB3A; ras-like low molecular mass GTP-binding protein; Ras-related small GTP binding protein 3A; small GTP-binding protein Rab3C; small GTPase; unnamed protein product

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基因别名: 2610528C18Rik; 2700062I01Rik; 3110015B08Rik; 3110037E15Rik; C130057E11Rik; D2-2; GOV; RAB16; RAB3; RAD3D; SCA52

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UniProt ID: (Human) P20336, (Human) P20337, (Human) Q96E17, (Human) O95716, (Rat) P63012, (Mouse) P63011, (Mouse) Q9CZT8, (Rat) Q63941, (Rat) P62824, (Mouse) P62823, (Rat) Q63942, (Mouse) P35276

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Entrez Gene ID: (Human) 5864, (Human) 5865, (Human) 115827, (Human) 9545, (Rat) 25531, (Mouse) 19339, (Mouse) 69908, (Rat) 81755, (Rat) 171058, (Mouse) 67295, (Rat) 140665, (Mouse) 19340

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功能
GTPase activity obsolete small monomeric GTPase activity protein binding GTP binding protein binding, bridging GTP-dependent protein binding myosin V binding GDP binding ATPase activator activity GDP-dissociation inhibitor binding ATPase binding
参与通路
exocytosis regulation of exocytosis peptidyl-cysteine methylation antigen processing and presentation positive regulation of dopamine uptake involved in synaptic transmission regulation of vesicle size regulation of synaptic vesicle cycle bone resorption positive regulation of regulated secretory pathway plasma membrane repair respiratory system process mitochondrion organization neuromuscular synaptic transmission axonogenesis post-embryonic development regulation of synaptic vesicle priming regulation of dopamine secretion synaptic vesicle exocytosis synaptic vesicle maturation calcium ion regulated exocytosis insulin secretion lung development regulation of synaptic vesicle fusion to presynaptic membrane lysosome localization Rab protein signal transduction synaptic vesicle recycling regulated exocytosis regulation of short-term neuronal synaptic plasticity synaptic vesicle transport maintenance of presynaptic active zone structure sensory perception of touch response to electrical stimulus acrosomal vesicle exocytosis evoked neurotransmitter secretion synaptic vesicle clustering regulation of presynaptic dense core granule exocytosis regulation of plasma membrane repair regulation of synaptic vesicle exocytosis constitutive secretory pathway positive regulation of exocytosis regulation of long-term synaptic potentiation
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