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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: PNSAPKAGLP GATGPMAVRP EEAVRGLGAG TESSRRAQEP VSGCGSPEQD PQKQAEEERQ EEPEYENVVP I
Highest antigen sequence indentity to the following orthologs: Mouse - 62%, Rat - 31%.
The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells and mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Transcription factors ZNF444/EZF-2 and SP1 are found to be responsible for the regulation of this gene. Five alternatively spliced transcript variants encoding distinct isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: acetyl LDL receptor; KIAA0149; MGC47738; scavenger receptor expressed by endothelial cells 1; unnamed protein product
基因别名: SREC; SREC-I; SREC1
UniProt ID: (Human) Q14162
Entrez Gene ID: (Human) 8578