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Invitrogen
SFTPD Polyclonal Antibody
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产品信息
PA5-149258
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Chinese hamster ovary cell line CHO-derived recombinant mouse SP-D, Ala20-Phe374
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
Surfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular 'head' regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Collectin7; CP4; Lung surfactant protein D; PSP-D; PSP-D Surfactant protein D; Pulmonary surfactant associated protein PSP-D; pulmonary surfactant protein D; Pulmonary surfactant-associated protein D; SFTP 4; surfactant associated protein D; Surfactant associated protein pulmonary 4; surfactant, pulmonary-associated protein D
基因别名: AI573415; Sftp4; Sftpd; SP-D; SPD
UniProt ID: (Rat) P35248, (Mouse) P50404
Entrez Gene ID: (Rat) 25350, (Mouse) 20390
respiratory gaseous exchange
opsonization
response to corticosteroid
negative regulation of interleukin-2 production
negative regulation of T cell proliferation
surfactant homeostasis
innate immune response
lung alveolus development
negative regulation of phagocytosis
positive regulation of phagocytosis
regulation of liquid surface tension
response to glucocorticoid
response to hyperoxia
response to growth factor
immune system process
