Invitrogen

SPDYA Polyclonal Antibody

Name: SPDYA Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-64267

高级验证

查看其他7个SPDYA抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (3)
高级验证 (1)

SPDYA Antibody in Immunohistochemistry (IHC)

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SPDYA Antibody (PA5-64267) in IHC

Immunohistochemical staining of SPDYA in human testis and fallopian tube tissues using SPDYA Polyclonal Antibody (Product # PA5-64267). Corresponding SPDYA RNA-seq data are presented for the same tissues.

Product Image Gallery

SPDYA Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of SPDYA demonstrates antibody specificity. Immunohistochemical analysis of SPDYA using anti-SPDYA Polyclonal Antibody (Product # PA5-64267), shows significant staining of SPDYA in human testis and shows minimal or weak staining in human fallopian tube tissues. The relative expression levels of SPDYA within each tissue is shown using RNA-Seq. {RE}

Immunogen image

Immunogen Image SPDYA Polyclonal Antibody

产品信息

PA5-64267

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:200-1:500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein fragment of Human SPDYA (Product #RP-104246).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2647827

产品详细信息

Immunogen sequence: CCEEVMAIAP THYIWQRERS VHHSGAVRNY NRDEVQLPRG PSATPVDCSL CGKKRRYVRL GLSSSSS

Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 94%.

靶标信息

Speedy A, also known as SPDYA, SPDY1, Ringo3 or SPY1, is a 313 amino acid protein that localizes to the nucleus and belongs to the speedy/ringo family. Expressed at high levels in testis and at lower levels in brain, kidney, heart, bone marrow, colon, lung, liver spleen and placenta, Speedy A functions to regulate the G1/S phase transition of the cell cycle, specifically by binding to and activating Cdc2 p34, Cdk2 and p27. Additionally, Speedy A mediates cell survival during DNA damage, suggesting that Speedy A plays a role in proper cell cycle progression throughout the life of the cell. Multiple isoforms of Speedy A exist due to alternative splicing events. The gene encoding Speedy A maps to human chromosome 2, which encodes over 1,400 genes and comprises nearly 8% of the human genome.

仅用于科研。不用于诊断过程。未经明确授权不得转售。