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Invitrogen
TRAIL-R3 Polyclonal Antibody
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TRAIL-R3 Antibody (PA5-88119) in WB
Western blot analysis of TRAIL-R3 in extracts of various cell lines. Samples were incubated with TRAIL-R3 Polyclonal antibody (Product # PA5-88119) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s.
产品信息
PA5-88119
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 150-238 of human TNFRSF10C (NP_0038322)
偶联物
形式
Liquid
浓度
0.51 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: VEEFGANATV ETPAAEETMN TSPGTPAPAA EETMNTSPGT PAPAAEETMT TSPGTPAPAA EETMTTSPGT PAPAAEETMT TSPGTPASS
Positive Samples: LO2, Mouse lung, Rat lung; Cellular Location: Cell membrane, GPI-anchor, Lipid-anchor
靶标信息
TRAIL-R3 (CD263) is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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