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Invitrogen
TSPAN8 Monoclonal Antibody (657909)
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FIGURE: 1 / 3
TSPAN8 Antibody (MA5-24296) in IHC (F)
Immunohistochemical analysis of TSPAN8 in perfusion fixed frozen sections of mouse intestine. Samples were incubated with TSPAN8 monoclonal antibody (Product # MA5-24296) using a dilution of 8 µg/mL overnight at 4 °C followed by NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (yellow) and counterstained with DAPI (blue). Specific staining was localized to membranes of epithelial cells.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-24296
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Published species
Mouse
Host/Isotype
Rat
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
657909
Immunogen
CHO Chinese hamster ovary cell line transfected with mouse TSPAN8
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
0.5 mg/mL once reconstituted
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody detects mouse TSPAN8 transfectants but not the parental cell line in flow cytometry.
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
Target Information
TSPAN8 (tetraspanin 8), also known as TM4SF3 or CO-029, is a 237 amino acid multi-pass membrane protein that belongs to the tetraspanin family of transmembrane proteins and is thought to play a role in signal transduction events that influence cell development, activation, growth and motility. Localized to the cell membrane, TSPAN8 is expressed in colon, gastric, renal and pancreatic cancers, strongly suggesting a role in cancer formation and metastasis. The gene encoding TSPAN8 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Tetraspanin8; transmembrane 4 superfamily member 3; tspan-8
Gene Aliases: E330007O21Rik; Tm4sf3
UniProt ID: (Mouse) Q8R3G9
Entrez Gene ID: (Mouse) 216350
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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