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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: QHIIPFRTYV IRYLCKLSDQ ELRQSAARNM ADLMWSTVKE PLDTTLCFDK ESLDLAFKYF MSPTLTMRLA GLSQITNQLH TFNDVCNNES LVSDTETSIA KELADWLI
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 21%.
Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: deubiquitinating enzyme 34; ubiquitin specific protease 34; ubiquitin thioesterase 34; ubiquitin thiolesterase 34; ubiquitin-specific-processing protease 34; unnamed protein product
UniProt ID: (Human) Q70CQ2
Entrez Gene ID: (Human) 9736