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Invitrogen
USP36 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-65745
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.05 mg/mL
规格
5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: EDGHLKCPRSA KPQDAVVPES SSCAPSANGW CPGDRMGLSQ APPVSWNGER ESDVVQELLK YSSDKAYGRK VLTWDGKMSA VSQDAIEDSR QARTETVVDD WDEEFDRGKE KKIKKFKREK RRNFNAFQKL QTRRNFWSVT HPAK
Highest antigen sequence identity to the following orthologs - mouse 70%, rat 68%.
靶标信息
May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: deubiquitinating enzyme 36; ubiquitin specific protease 36; ubiquitin thioesterase 36; ubiquitin-specific-processing protease 36; unnamed protein product
基因别名: DUB1
UniProt ID: (Human) Q9P275
Entrez Gene ID: (Human) 57602
chromatin organization
chromatin remodeling
nucleolus organization
negative regulation of macroautophagy
protein deubiquitination
regulation of protein stability
regulation of apoptotic process
protein stabilization
regulation of mitophagy
positive regulation of establishment of protein localization to mitochondrion
regulation of rRNA processing
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