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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: LLHGNTMEKLI KKRNVPQKLS PHSKRPDILK TESLLPKLDA ALSGVGLPGC PKGPPSPGRS RRGKTRHRKA SAKGSCGDL
Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.
ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DLK; Dual leucine zipper bearing kinase; Leucine-zipper protein kinase; M3KC; MAPK-upstream kinase; Mitogen-activated protein kinase kinase kinase 12; Mixed lineage kinase; MUK; ZPK
基因别名: MAP3K12; ZPK
Entrez Gene ID: (Human) 7786