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Proteintech
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Immunogen sequence: EQDLQLEEL RQQVSTLKCQ NEQLQTAVTQ QVSQIQQHKD QYNLLKIQLG KDNQHQGSYS EGAQMNGIQP EEIGRLREEI EELKRNQELL QSQLTEKDSM IENMKSSQTS GTNEQSSAIV SARDSEQVAE LKQELATLKS QLNSQSVEIT KLQTEKQELL QKTEAFAKSV EVQGETETII ATKTTDVEGR LSALLQETKE LKNEIKALSE ERTAIKEQLD SSNSTIAILQ TEKDKLELEI TDSKKEQDDL LVLLADQDQK ILSLKNKLKD LGHPVEEEDE LESGDQEDED DESEDPGKDL DHI
The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: General vesicular transport factor p115; Protein USO1 homolog; TAP; transcytosis associated protein; transcytosis associated protein p115; Transcytosis-associated protein; USO1 homolog, vesicle docking protein; USO1 vesicle docking protein homolog; VDP p115; vesicle docking protein p115; vesicle docking protein, 115 kDa; Vesicle-docking protein
基因别名: 115kDa; P115; TAP; USO1; VDP
UniProt ID: (Human) O60763, (Mouse) Q9Z1Z0, (Rat) P41542
Entrez Gene ID: (Human) 8615, (Mouse) 56041, (Rat) 56042