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Human BCMA/TNFRSF17 quantitates human BCMA/TNFRSF17 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human BCMA/TNFRSF17.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : BCM, BCMA, CD269, TNFRSF13A
基因ID : (Human) 608
基因符号 : TNFRSF17
蛋白别名 : alternatively spliced, lacks exon 2, B cell maturation antigen, B-cell maturation factor, B-cell maturation protein
UniProt ID (Human) Q02223