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Human Kininogen quantitates human Kininogen in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Kininogen.
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : BDK, BK, HAE6, HK, HMWK, KNG
基因ID : (Human) 3827
基因符号 : KNG1
蛋白别名 : alpha-2-thiol proteinase inhibitor, bradykinin, fitzgerald factor, high molecular weight kininogen, prepro alpha-2-thiol proteinase inhibitor, unnamed protein product, williams-Fitzgerald-Flaujeac factor
UniProt ID (Human) P01042