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Human Nectin-2/CD112 quantitates human Nectin-2/CD112 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Nectin-2/CD112.
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : CD112, HVEB, PRR2, PVRL2, PVRR2
基因ID : (Human) 5819
基因符号 : NECTIN2
蛋白别名 : herpesvirus entry protein B, HveB, poliovirus receptor-like 2, poliovirus receptor-related 2 (herpesvirus entry mediator B), PVRL2, unnamed protein product
UniProt ID (Human) Q92692