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Monkey GDF-15 quantitates monkey GDF-15 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant monkey GDF-15.
GDF-15 belongs to the TGF-beta cytokine family, whose members play an important role during prenatal development and postnatal growth, and the remodeling and maintenance of a variety of tissues and organs. GDF-15 is expressed predominantly in the placenta and, to a much lesser extent, in various other tissues. The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest GDF-15's involvement in gestation and embryonic development. GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway. Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certain colorectal, pancreatic, and prostate cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : GDF-15, HG, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB
基因ID : (Human) 9518
基因符号 : GDF15
蛋白别名 : macrophage inhibitory cytokine 1, NAG1, non-steroidal anti-inflammatory drug-activated gene-1, NRG-1, NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1, NSAID-activated gene 1 protein, NSAID-regulated gene 1 protein, PDF, placental bone morphogenetic protein, placental TGF-beta, prostate differentiation factor, PTGF-beta, TGF-b superfamily cytokine, unnamed protein product
UniProt ID (Human) Q99988