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Invitrogen
CTGF Recombinant Protein
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Product Details
RP-8618
Product Specifications
Expression System
E. coli
Class
Recombinant
Type
Protein
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
0.1 mg/mL
Amount
20 µg
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Recombinant human CTGF is a non-glycosylated protein, containing 98 amino acids, with a molecular weight of 11.2 kDa. Purity is typically greater than 98% and endotoxin level less than 1 EU/ug.
The expected biological activity (ED50) is determined by the dose-dependent stimulation of HUVEC proliferation and is typically 1-2 µg/mL. The specific activity of this protein is 6.7x10^2 units/mg.
Reconstitute using sterile 5mM sodium acetate, pH 6.0 at 0.1 mg/mL and centrifuge prior to opening vial. Gently pipet solution down the sides of the vial. DO NOT VORTEX sample. Store reconstituted material at -20°C and add 0.1% BSA for additional stability.
Amino acid sequence: MGKKCIRTPK ISKPIKFELS GCTSMKTYRA KFCGVCTDGR CCTPHRTTTL PVEFKCPDGE VMKKNMMFIK TCACHYNCPG DNDIFESLYY RKMYGDMA.
Target Information
Connective Tissue Growth Factor (CTGF), also called CCN2, is a member of the CCN family. CTGF is a secreted protein produced by umbilical veins and vascular endothelial cells. CTGF possesses an Insulin-like Growth Factor (IGF)-binding domain, a thrombospondin type 1 domain, and a cysteine knot region. CTGF plays important roles in the proliferation and differentiation of chondrocytes, induces angiogenesis, and promotes cell adhesion in fibroblasts, endothelial, and epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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