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Gibco
Human IL-12 p80 Recombinant Protein, PeproTech®
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产品信息
200-12P80H-10UG
产品规格
种属
Human
已发表种属
Human
Expression System
Insect cells
氨基酸序列
p40 subunit: IWELKKDVYV VELDWYPDAP GEMVVLTCDT PEEDGITWTL DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEVLSHSLL LLHKKEDGIW STDILKDQKE PKNKTFLRCE AKNYSGRFTC WWLTTISTDL TFSVKSSRGS SDPQGVTCGA ATLSAERVRG DNKEYEYSVE CQEDSACPAA EESLPIEVMV DAVHKLKYEN YTSSFFIRDI IKPDPPKNLQ LKPLKNSRQV EVSWEYPDTW STPHSYFSLT FCVQVQGKSK REKKDRVFTD KTSATVICRK NASISVRAQD RYYSSSWSEW ASVPCS
分子量
80 kDa
分类
Recombinant
类型
Protein
纯度
≥ 95% by SDS-PAGE gel and HPLC analyses.
内毒素浓度
<1 EU/µg
偶联物
形式
Lyophilized
纯化类型
purified
内含物
no preservative
保存条件
-20°C
运输条件
Ambient
产品详细信息
200-12P80H-1MG will be provided as 10 x 100 µg (200-12P80H-100UG).
200-12P80H-250UG will be provided as multiple 50 µg (200-12P80H-50UG) and 100 µg (200-12P80H-100UG) vials.
200-12P80H-500UG will be provided as 5 x 100 µg (200-12P80H-100UG).
Recombinant Human IL-12 p80 is an 80.0 kDa disulfide linked homodimer consisting of two p40 chains of IL-12.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
靶标信息
IL-12 is a disulfide-linked heterodimeric protein (p70), composed of two subunits, p35 and p40, which are encoded by two different genes. Accumulating data indicates that p40 secretion precedes that of IL-12 expression. In addition, to its ability to covalently bind to p35 to form IL-12, p40 can bind to p19 to form IL-23, or it can form the homodimer designated IL-12 p80. Elevated levels of IL-12 p80 correlate to macrophage recruitment and increased inflammation in asthma and respiratory viral infection models.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CLMF p40; Cytotoxic lymphocyte maturation factor 40 kDa subunit; IL-12; IL-12 subunit p40; IL-12B; IL12, subunit p40; Interleukin; interleukin 12, p40; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); interleukin-12 beta chain; Interleukin-12 subunit beta; natural killer cell stimulatory factor, 40 kD subunit; NK cell stimulatory factor chain 2; NKSF2
基因别名: CLMF; CLMF2; IL-12B; IL12B; IMD28; IMD29; NKSF; NKSF2
UniProt ID: (Human) P29460
Entrez Gene ID: (Human) 3593
