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Highest antigen sequence indentity to the following orthologs: Mouse (31%), Rat (31%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67226. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene is a MAGE-B subfamily member of the MAGE gene family. MAGE family member proteins direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. There are two known clusters of MAGE genes on chromosome X. The members of the MAGE-A subfamily are located in the Xq28 region, while the members of the MAGE-B subfamily are clustered in the Xp21 region.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: cancer/testis antigen family 3, member 5; MAGE-B3 antigen; melanoma antigen family B, 3; melanoma antigen family B3; Melanoma-associated antigen B3
基因别名: CT3.5; MAGEB3
UniProt ID: (Human) O15480
Entrez Gene ID: (Human) 4114