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Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84447. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
MYT1L, myelin transcription factor 1 family, to which the myelin transcription factor 1-like protein (MYT1L) belongs, is expressed primarily in the developing central nervous system and recruits histone deacetylase (HDAC) to regulate neural transcription. Both MYT1L and the related protein MYT1 interact with SIN3B, a protein that mediates transcriptional repression by binding to HDACs, suggesting that the MYT1 family favor the silencing of genes during neural development. Recent studies suggest that polymorphisms of MYT1L may be associated with schizophrenia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Myelin transcription factor 1-like protein; MyT1-L; neural zinc finger transcription factor 1
基因别名: KIAA1106; MRD39; MYT1L; NZF1; ZC2H2C2; ZC2HC4B
UniProt ID: (Human) Q9UL68
Entrez Gene ID: (Human) 23040