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5HT4 R Polyclonal Antibody
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图: 1 / 9
5HT4 R Antibody (OSS00421W-100UL) in IHC (P)
IHC-P on paraffin sections of mouse spleen. The animal was perfused using Autoperfuser at a pressure of 130 mmHg with 300 mL 4% FA being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions; DAB chromogen: Candela DAB chromogen ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
OSS00421W-100UL
产品规格
种属反应
Human,
Mouse,
Non-human primate
宿主/亚型
Rabbit
/ Ig
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from human 5HT4 R conjugated to blue carrier protein was used as the antigen
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
Conc. Not Determined
保存液
whole serum
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: 5HT4 receptor.
靶标信息
This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described, but the full-length nature of some transcript variants has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 5-HT4 receptor; 5-HT4b; G protein-coupled; 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled; 5HT4; 5HT4 receptor; cardiac 5-HT4 receptor; unnamed protein product
基因别名: 5-HT-4; 5-HT4; 5-HT4R; 5-HT<4L>; 5HTR4
UniProt ID: (Human) Q13639, (Mouse) P97288
Entrez Gene ID: (Human) 3360, (Mouse) 15562
system process
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-activating serotonin receptor signaling pathway
adenylate cyclase-inhibiting serotonin receptor signaling pathway
gamma-aminobutyric acid signaling pathway
chemical synaptic transmission
maintenance of gastrointestinal epithelium
regulation of appetite
mucus secretion
large intestinal transit
regulation of postsynapse assembly
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
