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Immunogen sequence: LGNYDEMKDF IGDRSIPKLV AIPKPTVPPS ADEKSNPNFF EQRHGGSHQS SKWTPVGPAP STSQSQKRSS GLQSGHSSQR TSAGSSSGTN SSGQRHDRES YNNSGSSSRK KGQHGSEHSK SRSSSPGKPQ AVSSLNSSHS RSHG
The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AF4/FMR2 family member 4; AF4/FMR2 family, member 4; ALL1-fused gene from chromosome 5q31 protein; Major CDK9 elongation factor-associated protein; Protein AF-5q31
基因别名: AF5Q31; AFF4; CHOPS; HSPC092; MCEF
UniProt ID: (Human) Q9UHB7
Entrez Gene ID: (Human) 27125
分子生物学功能:
DNA-binding transcription factor