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Proteintech
API5 Polyclonal Antibody
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产品信息
25689-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
API5 Fusion Protein Ag22524 (155-504 aa encoded by BC017709)
偶联物
形式
Liquid
浓度
0.22 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LSTKLKTLP DEVLTKEVEE LILTESKKVL EDVTGEEFVL FMKILSGLKS LQTVSGRQQL VELVAEQADL EQTFNPSDPD CVDRLLQCTR QAVPLFSKNV HSTRFVTYFC EQVLPNLGTL TTPVEGLDIQ LEVLKLLAEM SSFCGDMEKL ETNLRKLFDK LLEYMPLPPE EAENGENAGN EEPKLQFSYV ECLLYSFHQL GRKLPDFLTA KLNAEKLKDF KIRLQYFARG LQVYIRQLRL ALQGKTGEAL KTEENKIKVV ALKITNNINV LIKDLFHIPP SYKSTVTLSW KPVQKVEIGQ KRASEDTTSG SPPKKSSAGP KRDARQIYNP PSGKYSSNLG NFNYERSLQG K (155-504 aa encoded by BC017709)
靶标信息
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: AAC-11; Antiapoptosis clone 11 protein; API-5; Apoptosis inhibitor 5; Cell migration-inducing gene 8 protein; Fibroblast growth factor 2-interacting factor; fibroblast growth factor 2-interacting factor 2; FIF; FIF C1; migration-inducing protein MIG8; Protein XAGL
基因别名: AAC-11; AAC11; AI196452; API-5; API5; MIG8
UniProt ID: (Human) Q9BZZ5, (Mouse) O35841
Entrez Gene ID: (Human) 8539, (Mouse) 11800
