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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: antiapoptosis clone 11 protein; apoptosis inhibitory protein 5; cell migration-inducing gene 8 protein; fibroblast growth factor 2-interacting factor 2; FIF; FIF C1; FIF, AAC-11, API5-L1, XAGL; migration-inducing protein MIG8; putative; unnamed protein product
基因别名: AAC-11; AAC11; API-5
UniProt ID: (Human) Q9BZZ5, (Mouse) O35841
Entrez Gene ID: (Human) 8539, (Mouse) 11800