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Invitrogen
ARHGAP32 Polyclonal Antibody
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产品信息
PA5-58369
产品规格
种属反应
Human
已发表种属
C. elegans
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human p190-A RhoGAP. Recombinant protein control fragment (Product #RP-97354).
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: ERDPSVLYQY QPHGKRQSSV TVVSQYDNLE DYHSLPQHQR GVFGGGGMGT YVPPGFPHPQ SRTYATALGQ GAFLPAELSL QHPETQIHAE
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 88%.
靶标信息
GTPase-activating protein (GAP) promoting GTP hydrolysis on RHOA, CDC42 and RAC1 small GTPases. May be involved in the differentiation of neuronal cells during the formation of neurite extensions. Involved in NMDA receptor activity-dependent actin reorganization in dendritic spines. May mediate cross-talks between Ras- and Rho regulated signaling pathways in cell growth regulation. Isoform 2 has higher GAP activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: brain-specific Rho GTP-ase-activating protein; Brain-specific Rho GTPase-activating protein; GAB-associated CDC42; GAB-associated Cdc42/Rac GTPase-activating protein; GC-GAP; GTPase regulator interacting with TrkA; GTPase-activating protein for Cdc42 and Rac1; p200RhoGAP; p250GAP; rac GTPase activating protein; Rho GTPase-activating protein 32; Rho-type GTPase-activating protein 32; Rho/Cdc42/Rac GTPase-activating protein RICS; RhoGAP involved in the -catenin-N-cadherin and NMDA receptor signaling; RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling
基因别名: ARHGAP32; GC-GAP; GRIT; KIAA0712; p200RhoGAP; p250GAP; PX-RICS; RICS
UniProt ID: (Human) Q86YL6
Entrez Gene ID: (Human) 9743
