Search Thermo Fisher Scientific
Immunogen sequence: FRDKVLGYFW NRQHSQRHSS TNLLQEGLGS HRTQVPHLSL GPRPPTPPCA VTKTLSASHR TCYLVTQL
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 76%.
ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.
仅用于科研。不用于诊断过程。未经明确授权不得转售。