NIP1 (BNIP1) is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. Alternative splicing of this gene results in four products of unknown function. Transcript variant BNIP1 contains the entire coding region of the gene. This variant contains a fully conserved BH3 domain, which has been associated with pro-apoptotic function.
蛋白别名: BCL2/adenovirus E1B 19 kDa protein-interacting protein 1; BCL2/adenovirus E1B 19kDa interacting protein 1; Transformation-related gene 8 protein; TRG-8; Vesicle transport protein SEC20
基因别名: BNIP1; NIP1; SEC20; SEC20L; TRG-8; TRG8
UniProt ID: (Human) Q12981
Entrez Gene ID: (Human) 662