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Proteintech
CCSAP Polyclonal Antibody
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产品信息
28644-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein
偶联物
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: MSPGSGVKSE YMKRYQEPRW EEYGPCYREL LHYRLGRRLL EQAHAPWLWD DWGPAGSSED SASSESSGAG GPAPRCAPPS PPPPVEPATQ EEAERRARGA PEEQDAEAGD AEAEDAEDAA LPALPVKDVE DKPEQQTRTR ETDKSPTSTE PRQQPSALFA RGNRKAVKSP QRSSSKIKEN KHPFALYGWG EKQTDTGSQK THNVCASAPV HEIHESALRA KNRRQVEKRK LVAQRQRAHS VDVEKNRKMK ASSSENPWMT EYMRCYSARA
靶标信息
Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle (PubMed:26562023). May play a role in embryonic development. May be required for proper cilia beating. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: centriole and spindle-associated protein; Centriole, cilia and spindle-associated protein
基因别名: 1700054N08Rik; AI853424; C1orf96; CCSAP; CSAP; RGD1563235
UniProt ID: (Human) Q6IQ19, (Mouse) Q8QZT2
Entrez Gene ID: (Human) 126731, (Rat) 307926, (Mouse) 73420
