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Invitrogen
CD11c Recombinant Rabbit Monoclonal Antibody (1N6N9)
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FIGURE: 1 / 3
CD11c Antibody (MA575300) in ICC/IF
Immunocytochemistry analysis of CD11c in THP-1 cells (treated with PMA) and THP-1 cells (untreated). Samples were incubated with monoclonal CD11c (Product # MA575300) antibody at a dilution of 1:200, followed by Cy3-conjugated Goat anti-Rabbit IgG (H+L) (1:500) (Red) and DAPI. Objective: 100x.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA575300
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
1N6N9
Immunogen
Recombinant protein (or fragment).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.41 mg/mL
Amount
41 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 0.05% BSA, 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
CD11, along with CD18, form a heterodimer adhesion molecule. In particular, CD11 is composed of CD11a, CD11b and CD11c. CD11a is a leukocyte marker that is expressed in B and T lymphocytes, macrophages, monocytes, neutrophils, basophils and eosinophils. CD11b is primarily expressed by monocytes, macrophages, natural killer cells, some B and T-cells, and granulocytes. CD11c is expressed in monocytes, macrophages, natural killer cells, some granulocytes and less so in a subset of lymphocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD11 antigen-like family member C; CD11c; CD11C (p150) alpha polypeptide; complement component 3 receptor 4 subunit; complement receptor 4; integrin alpha X; integrin aX; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); integrin; protein p150,95; leu M5, alpha subunit; leukocyte adhesion glycoprotein p150,95 alpha chain; leukocyte adhesion receptor p150,95; leukocyte surface antigen p150,95, alpha subunit; myeloid membrane antigen, alpha subunit; p150 95 integrin alpha chain; unnamed protein product
Gene Aliases: CD11C; Cr4; N418; SLEB6
UniProt ID: (Human) P20702, (Mouse) Q9QXH4
Entrez Gene ID: (Human) 3687, (Mouse) 16411
phagocytosis
cell adhesion
leukocyte cell-cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
positive regulation of cell proliferation
positive regulation of gene expression
positive regulation of cell migration
positive regulation of myelination
cell-cell adhesion mediated by integrin
heterotypic cell-cell adhesion
positive regulation of angiogenesis
defense response to virus
cell-cell adhesion
positive regulation of endothelial tube morphogenesis
organ morphogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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