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Invitrogen
CD264 (TRAIL-R4) Monoclonal Antibody (TRAIL-R4-01), Alexa Fluor™ 647
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CD264 (TRAIL-R4) Antibody (MA562265) in Flow
Flow cytometry (surface staining) of CD264 (TRAIL-R4) in CD264 transfected HEK-293 cells. Samples were stained with CD264 (TRAIL-R4) monoclonal antibody (Product # MA562265) using a dilution of 5 µg/mL. Separation of stained CD264 transfected HEK-293 cells (red-filled) from CD264 transfected HEK-293 cells stained using mouse IgG1 isotype control (MOPC-21) Alexa Fluor® 647 antibody (5 µg/mL, black-dashed).
产品信息
MA562265
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
TRAIL-R4-01
抗原
TRAIL-R4 (aa 1-210) - hIgGhc fusion protein.
偶联物
激发/发射光谱
650/671 nm
查看光谱
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Size-exclusion chromatography
保存液
PBS, pH 7.4, with 0.2% BSA
内含物
15mM sodium azide
保存条件
4°C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A fourth member of the emerging TRAIL receptor family, TRAIL-R4, has signaling capacity similar to that of TRAIL-R1 and TRAIL-R2 with respect to NF-kappaB activation, but differs in its inability to induce apoptosis. Like TRAIL-R1 and TRAIL-R2, this receptor shows widespread tissue expression. The human TRAIL-R4 gene has been mapped to chromosome 8p22-21, clustered with three other TRAIL receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD264; DcR2; Decoy receptor 2; TNF receptor-related receptor for TRAIL; TNF-related apoptosis-inducing ligand receptor 4; TRAIL receptor 4; TRAIL receptor with a truncated death domain; Tumor necrosis factor receptor superfamily member 10D; tumor necrosis factor receptor superfamily member 10d, decoy with truncated death domain; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
基因别名: CD264; DCR2; TNFRSF10D; TRAIL-R4; TRAILR4; TRUNDD; UNQ251/PRO288
UniProt ID: (Human) Q9UBN6
Entrez Gene ID: (Human) 8793
inflammatory response
immune response
signal transduction
multicellular organism development
extrinsic apoptotic signaling pathway via death domain receptors
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
regulation of cell proliferation
regulation of apoptotic process
negative regulation of apoptotic process
