应用 | 建议稀释比 | 已发表文章 |
---|---|---|
流式细胞分析 (Flow) |
Neat | - |
产品规格 | |
---|---|
种属反应 |
Human, Non-human primate |
宿主/亚型 |
Rat / IgG2b |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
YTH34.5 |
抗原 |
human lymphocytes |
偶联物 |
PE
|
激发/发射光谱 |
查看光谱 |
形式 |
Lyophilized |
浓度 |
Conc. Not Determined |
纯化类型 |
Protein A |
保存液 |
PBS with 1% BSA, 5% sucrose |
内含物 |
0.09% sodium azide |
保存条件 |
4° C, store in dark, DO NOT FREEZE! |
RRID |
AB_2538474 |
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
Reconstitute using 0.25 mL distilled water.
Rat anti Human CD52 antibody, clone YTH34.5 reacts with the human CD52 antigen, also known as CAMPATH-1.
Human CD52, also known as Cambridge pathology antigen 1 (CAMPATH-1), is a glycoprotein found in the male reproductive tract and immune cells. It is abundantly expressed on the surface of nearly all human peripheral blood lymphocytes. The CD52 antigen is GPI-anchored membrane receptor that consists of a small 12 amino acid peptide attached to a large N-linked carbohydrate group. CD52 is a potent target for inducing cytolysis of mature lymphocytes. Alemtuzumab, a humanized monoclonal antibody targeting CD52, is used as an immunomodulatory drug for the treatment of chronic lymphocytic leukemia, T cell lymphomas, multiple sclerosis, and other diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
蛋白别名: Cambridge pathology 1 antigen; CAMPATH-1 antigen; CD52; CD52 antigen; CD52 antigen (CAMPATH-1 antigen); CDw52; CDW52 antigen (CAMPATH-1 antigen); Epididymal secretory protein E5; epididymis secretory sperm binding protein Li 171mP; He5; HEL-S-171mP; Human epididymis-specific protein 5
基因别名: CD52; CDW52; HE5
UniProt ID: (Human) P31358
Entrez Gene ID: (Human) 1043