Invitrogen

CD69 Monoclonal Antibody (CH/4), FITC

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CD69 Antibody (MHCD6901) in Flow

Journal of medical virology 2013 - Published figure using CD69 monoclonal antibody (Product # MHCD6901) in Flow Cytometry

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产品信息

MHCD6901

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

Assay-Dependent

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其他PubMed (Misc)

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产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Mouse / IgG2a

分类

Monoclonal

类型

Antibody

克隆号

CH/4

抗原

Human CD69

偶联物

FITC

激发/发射光谱

498/517 nm 查看光谱

形式

Liquid

纯化类型

purified

保存液

PBS with BSA

内含物

0.1% sodium azide

保存条件

4° C, store in dark

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_10373831

产品详细信息

Commonly used, FITC conjugates provide relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility.

靶标信息

CD69 (AIM, Active Inducer Molecule) is a gp28/34 disulfide bonded homodimer with a molecular weight of 60 kDa under non-reducing conditions. CD69 contains one or two N linked oligosacaride and the molecule is present on activated platelets. In normal peripheral blood a variable percentage of cells express the CD69 antigen, and it is involved in lymphocyte signal transduction. Expression CD69 is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. Alternative splicing results in multiple transcript variants of CD69. Diseases associated with CD69 dysfunction include coccidiodomycosis and asthma.

Analyte Specific Reagent

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Product References

Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor.

The Journal of clinical investigation

MacDonald KG,Hoeppli RE,Huang Q,Gillies J,Luciani DS,Orban PC,Broady R,Levings MK

MHCD6901 was used in flow cytometry develop an HLA-A2-specific chimeric antigen receptor and use it to generate alloantigen-specific human T regulatory cells

Fri Apr 01 00:00:00 EDT 2016

Enhanced Cytotoxic CD8 T Cell Priming Using Dendritic Cell-Expressing Human Papillomavirus-16 E6/E7-p16INK4 Fusion Protein with Sequenced Anti-Programmed Death-1.

Journal of immunology (Baltimore, Md. : 1950)

Garcia-Bates TM,Kim E,Concha-Benavente F,Trivedi S,Mailliard RB,Gambotto A,Ferris RL

MHCD6901 was used in flow cytometry to generate adenoviral vaccines that express HPV-16 E6 and E7 epitopes alone or fused with p16 and assess immune responses

Tue Mar 15 00:00:00 EDT 2016

Anti-inflammatory/regulatory cytokine microenvironment mediated by IL-4 and IL-10 coordinates the immune response in hemophilia A patients infected chronically with hepatitis C virus.

Journal of medical virology

Pimentel JP,Chaves DG,Araújo AR,de Araújo EM,da Silva Fraporti L,Neves WL,Tarragô AM,Torres KL,Gentz SH,Teixeira-Carvalho A,Martins-Filho OA,Malheiro A

Published figure using CD69 monoclonal antibody (Product # MHCD6901) in Flow Cytometry

Sat Jun 01 00:00:00 EDT 2013

Immunological/virological peripheral blood biomarkers and distinct patterns of sleeping quality in chronic hepatitis C patients.

Scandinavian journal of immunology

de Almeida CM,de Lima TA,Castro DB,Torres KL,da Silva Braga W,Peruhype-Magalhães V,Teixeira-Carvalho A,Martins-Filho OA,Malheiro A

MHCD6901 was used in flow cytometry to identify immunological/virological biomarkers associated with sleep quality in patients with chronic hepatitis C.

Sun May 01 00:00:00 EDT 2011

Abnormal cell surface antigen expression in individuals with variant CD45 splicing and histiocytosis.

Pediatric research

Boxall S,McCormick J,Beverley P,Strobel S,De Filippi P,Dawes R,Klersy C,Clementi R,De Juli E,Ferster A,Wallace D,Aricò M,Danesino C,Tchilian E

MHCD6901 was used in Flow cytometry/Cell sorting to study abnormal cell surface antigen expression in individuals with variant CD45 splicing and histiocytosis.

Mon Mar 01 00:00:00 EST 2004

Human CD4+CD25+ regulatory cells have marked and sustained effects on CD8+ T cell activation.

European journal of immunology

Câmara NO,Sebille F,Lechler RI

MHCD6901 was used in flow cytometry to study the interactions between CD4(+)CD25(+) T cells and human CD8(+) T cells.

Mon Dec 01 00:00:00 EST 2003

生物信息学

蛋白别名: Activation inducer molecule; activation inducer molecule (AIM/CD69); AIM; BL-AC/P26; C-type lectin domain family 2 member C; C-type lectin domain family 2, member C; CD69; CD69 antigen (p60, early T-cell activation antigen); EA1; Early activation antigen CD69; early lymphocyte activation antigen; Early T-cell activation antigen p60; GP32/28; Leukocyte surface antigen Leu-23; MLR-3

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基因别名: AIM; BL-AC/P26; CD69; CLEC2C; EA1; GP32/28; MLR-3

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UniProt ID: (Human) Q07108

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Entrez Gene ID: (Human) 969

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功能

transmembrane signaling receptor activity calcium ion binding protein binding carbohydrate binding

参与通路

signal transduction cellular response to drug