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Invitrogen
CD89 Monoclonal Antibody (A59), PE
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产品信息
MA5-28547
应用
建议稀释比
已发表文章
产品规格
种属反应
Cynomolgus monkey,
Human,
Non-human primate,
Rhesus monkey
已发表种属
C. elegans
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
A59
抗原
Ag8.653 myeloma cells
偶联物
激发/发射光谱
565/576 nm
查看光谱
形式
Liquid
纯化类型
Size-exclusion chromatography
保存液
PBS, pH 7.4, with 0.2% BSA
内含物
15mM sodium azide
保存条件
4°C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody recognizes an extracellular epitope of CD89, a 55-100 kDa glycoprotein serving as a receptor for IgA and expressed mainly on granulocytes, monocytes and macrophages. Recommended dilution is for 100 µL of whole blood or 1x10^6 cells in suspension.
靶标信息
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
生物信息学
蛋白别名: CD89; Fc alpha receptor; Fc fragment of IgA, receptor for; IgA Fc receptor; immunoglobulin A Fc receptor; immunoglobulin A Fc receptor transcript variant deltaEC1 delta TM/C; Immunoglobulin alpha Fc receptor
基因别名: CD89; CTB-61M7.2; FcalphaRI; FCAR
UniProt ID: (Human) Q1AJL9
Entrez Gene ID: (Cynomolgus monkey) 102145896, (Human) 2204, (Rhesus monkey) 664734
