Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
H00000976-M13
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
3B11
抗原
CD97 (AAH26690, 1 a.a. approximately 742 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: MGGRVFLAFC VWLTLPGAET QDSRGCARWC PQNSSCVNAT ACRCNPGFSS FSEIITTPTE TCDDINECAT PSKVSCGKFS DCWNTEGSYD CVCSPGYEPV SGAKTFKNES ENTCQDVDEC SSGRHQCDSS TVCFNTVGSY SCRCRPGWKP RHGIPNNQKD TVCEDMTFST WTPPPGVHSQ TLSRFFDKVQ DLGRDSKTSS AEVTIQNVIK LVDELMEAPG DVEALAPPVR HLIATQLLSN LEDIMRILAK SLPKGPFTYI SPSNTELTLM IQERGDKNVT MGQSSARMKL NWAVAAGAED PGPAVAGILS IQNMTTLLAN ASLNLHSKKQ AELEEIYESS IRGVQLRRLS AVNSIFLSHN NTKELNSPIL FAFSHLESSD GEAGRDPPAK DVMPGPRQEL LCAFWKSDSD RGGHWATEGC QVLGSKNGST TCQCSHLSSF AILMAHYDVE DWKLTLITRV GLALSLFCLL LCILTFLLVR PIQGSRTTIH LHLCICLFVG STIFLAGIEN EGGQVGLRCR LVAGLLHYCF LAAFCWMSLE GLELYFLVVR VFQGQGLSTR WLCLIGYGVP LLIVGVSAAI YSKGYGRPRY CWLDFEQGFL WSFLGPVTFI ILCNAVIFVT TVWKLTQKFS EINPDMKKLK KARALTITAI AQLFLLGCTW VFGLFIFDDR SLVLTYVFTI LNCLQGAFLY LLHCLLNKKV REEYRKWACL VAGGSKYSEF TSTTSGTGHN QTRALRASES GI
靶标信息
CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Adhesion G protein-coupled receptor E5; CD97; CD97 molecule; Leukocyte antigen CD97; seven transmembrane helix receptor; seven-span transmembrane protein; seven-transmembrane, heterodimeric receptor associated with inflammation
基因别名: ADGRE5; CD97; TM7LN1
UniProt ID: (Human) P48960
Entrez Gene ID: (Human) 976
