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Invitrogen
COMMD5 Polyclonal Antibody
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COMMD5 Antibody (PA5-100232) in ICC/IF
Immunofluorescent analysis of COMMD5 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and COMMD5 polyclonal antibody (Product # PA5-100232) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-100232
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human COMMD5(Accession Q9GZQ3), corresponding to amino acid residues M1-L43.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total COMMD5.
靶标信息
COMMD5 is a protein coding gene. May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis. Down-regulates activation of NF-kappa-B.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: COMM domain-containing protein 5; FLJ13008; HCaRG; hypertension-related calcium regulated; Hypertension-related calcium-regulated gene protein; hypertension-related, calcium regulated
基因别名: 2310065H03Rik; AI854466; COMMD5; D15Ertd81e; HCARG; HT002
UniProt ID: (Human) Q9GZQ3, (Rat) Q9ERR2, (Mouse) Q8R395
Entrez Gene ID: (Human) 28991, (Rat) 245974, (Mouse) 66398
