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Invitrogen
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PA3-107 detects the CPP-binding protein.
PA3-107 has been used successfully in Western blot, ELISA, immunoprecipitation, immunohistochemistry, and immunocytochemistry procedures. In Western blot analysis of rat brain synaptic membranes this antibody detects ~80 kDa and ~60 kDa proteins representing CPP-binding protein. The ~60kDa protein is likely a breakdown product of the ~80 kDa CPP-binding protein.
The PA3-107 immunogen is a synthetic peptide corresponding to the C-terminal residues K(396) A E P K R T T L G(405) C of rat CPP-binding protein.
CPP is a potent antagonist acting selectively at NMDA type excitatory amino acid receptors. This compound is more potent than previously reported NMDA antagonists in depressing mammalian spinal neuronal responses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。