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Abnova
CXorf20 Polyclonal Antibody, MaxPab™
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产品信息
H00139105-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CXorf20 (NP_699177.1, 1 a.a. approximately 799 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSERTQEQDF VIITVDDSDD NNDCSIEMVE VSETADNSTN DIADDSTYVT ADNPTDDTAT QPNFPGGNDG HHRPLQMSYG SGSVTQAGVQ WHDHSSLQPQ PLGLKQFFHL SLPSSWDDRR TPPCPVAHGD QIVSQINHPV HLRRYSYNSE EVDFPKRGRF YTPEVQSSIS PPAERQETHA WASPAVTSLE SAACHELQEA DLSESLSYPR IVSSSSLQQY VAQGGSFPCF GMPWNFISGG AESTNAVISF ANATTAVPMA VLSRRESSLA NNPGVVNYSA LPENENVGPG RALSSFCFHP NLEMPERPAN SSKNSTETAN YPTLMGNYNG QNTASLSVFI PPYFAEKIIL TEMPGTTETN VENNSQTVYY PALSGNTSAP YPASSYLPIT SNFESGPQMS YGTMSYSTEM KNNCDQDDAS ASACLTPDFA LLPLNILVKV DTNTENSVNT MNRSTLLDSD SGQDSSSSSV CIPPKYGYLG DPKRNVRVLK IHLLAVQNMA KPKQAACYLV RILFSKEILI SSSVDIHLKD SQSLDPNKMA ALREYLATTF PTCDLHEHGK DWQDCISGIN SMIYCLCSEG KSTPKTVRKN KKRTNRVASA SADRNDQRGR DGGEGCSWMF QPMNNSKMRV KRNLQPNSNA IPEGMREPST DNPEEPGEAW SYFGRPWRNI RMPCSVLTLA KTKSCASLSA RYLIQKLFTK DVLVQSNVYG NLKHGLCALD PNKISALREF LQENYPICDL SENGRDWKSC VTSINSGIRS LRHDVRRAEA RSQSLPAVTP PELEQESKPG DPDATDPST
靶标信息
The BEND2 gene, located on chromosome Xp22.2, encodes a protein that is part of the BEN domain-containing family, which is implicated in chromatin organization and transcriptional regulation. BEND2 is critical in spermatogenesis, particularly in the meiotic phase of germ cell development. Knockout studies in male mice have shown that loss of BEND2 disrupts the transition from zygonema to pachynema, interferes with chromosomal synapsis, and impairs the repair of DNA double-strand breaks, ultimately causing infertility. Additionally, BEND2's interaction with chromatin-associated proteins suggests its role in the formation of transcription-repressor complexes, essential for proper gene expression regulation during meiosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BEN domain-containing protein 2
基因别名: BEND2; CXorf20
UniProt ID: (Human) Q8NDZ0
Entrez Gene ID: (Human) 139105
