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Invitrogen
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Immunogen sequence: RHTMHVGRAG DAFGDTSFLN SKAGEPDGES LDEQPSSSSS KRSLLSRKFR GSKRSQSVTR GEREQRDMLG SLRDSALFVK NAMSLPQLNE KEAAEKGTSK
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 87%.
The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Binder of Rho GTPases 4; CDC42 effector protein (Rho GTPase binding) 4; Cdc42 effector protein 4; MGC17125; MGC3740
基因别名: BORG4; CDC42EP4; CEP4; KAIA1777
UniProt ID: (Human) Q9H3Q1
Entrez Gene ID: (Human) 23580