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产品信息
PA5-62993
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2640362
产品详细信息
Immunogen sequence: RKRSHHGLGF LCCFGGSDIP EINLRDNHPL QFMEFSSPIP NAEELNIRFA ELVDEL^M
^M
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 82%.
靶标信息
DAAM2 is a recently identified planar cell polarity (PCP) signaling molecule implicated in the regulation of cellular polarity, convergent extension, and invasion. DAAM2 belongs to the formin homology family and contains a DAD (diaphanous autoregulatory) domain, an FH1 (formin homology 1) domain, an FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/ formin homology 3) domain. The DAAM2 protein is known to be involved in cell divison. Though the exact function of DAAM2 is yet unknown, reports suggest that it is closely related to DAAM1 and hence along with DAAM1 it may also be required in Wnt/Fz signaling and activation of Rho and in regulating cytoskeleton architecture. DAAM2 is expressed in most of tissues but the expression level ishigher in brain.
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生物信息学
蛋白别名: Disheveled-associated activator of morphogenesis 2; dishevelled-associated activator of morphogenesis 2; RP1-278E11.1
基因别名: DAAM2; dJ90A20A.1; KIAA0381
UniProt ID: (Human) Q86T65
Entrez Gene ID: (Human) 23500
