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Invitrogen
DCAF4 Polyclonal Antibody
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产品信息
PA5-61485
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: TSSGTAGTSS VPELPGFYFD PEKKRYFRLL PGHNNCNPLT KESIRQKEME SKRLRLLQEE DRRK
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 80%.
靶标信息
The nuclear protein p100 is a proliferation-associated protein whose expression is restricted to cell cycle phases S, G2, and M. Exclusively expressed in proliferating cells from the transition G1/S until the end of cytokinesis. During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. The full-length cDNA encodes a 747-amino acid protein with a putative ATP/GTP-binding site motif. RT-PCR analysis demonstrated strong expression of in lung carcinoma cell lines but not in normal lung tissues. Expression was also found in adult placenta, skeletal muscle, thymus, testis, and small intestine and in fetal brain, liver, and kidney. P100 is also correlated to cancer prognosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DDB1- and CUL4-associated factor 4; DKFZp434K114; WD repeat domain 21A; WD repeat-containing protein 21A
基因别名: DCAF4; WDR21; WDR21A
UniProt ID: (Human) Q8WV16
Entrez Gene ID: (Human) 26094
