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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: QLGKRKRELD VEEAHAASTE EKEAGVGNGT CAPVRLPFSG FRLQKVLRES ARDKIIFLHG KVNEASGDGD GEDAVVILEK TPFQVEQVAQ LLTGSPE
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 82%.
Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3'->5' exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase; DCPS; decapping scavenger enzyme; epididymis secretory sperm binding protein; heat shock-like protein 1; HINT-5; hint-related 7meGMP-directed hydrolase; histidine triad nucleotide-binding protein 5; histidine triad protein member 5; homolog of C. elegans 7meGMP-directed hydrolase dcs-1; mRNA decapping enzyme; NADPH-dependent flavin reductase; scavenger mRNA-decapping enzyme DcpS
基因别名: ARS; DCS1; HINT-5; HINT5; HSL1; HSPC015
UniProt ID: (Human) Q96C86
Entrez Gene ID: (Human) 28960