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产品信息
PA5-64951
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫细胞化学 (ICC/IF) |
0.25-2 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant Human DDRGK1 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.05 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.2, with 40% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2664400 |
产品详细信息
Immunogen sequence: ASAGQEPLHNE ELAGAGRVAQ PGPLEPEEPR AGGRPRRRRD LGSRLQAQRR AQRVAWAEAD ENEEEAVIL
Highest antigen sequence identity to the following orthologs - mouse 68%, rat 70%.
靶标信息
Protein which interacts with the E3 UFM1-protein ligase UFL1 and one of its substrates TRIP4 and is required for TRIP4 ufmylation. Through TRIP4 ufmylation may regulate nuclear receptors-mediated transcription. May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIA, the inhibitor of NF-kappa-B. May also play a role in the cellular response to endoplasmic reticulum stress.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Dashurin; DDRGK domain-containing protein 1; UFM1-binding and PCI domain-containing protein 1; UFM1-binding protein 1 containing a PCI domain
基因别名: C20orf116; DDRGK1; dJ1187M17.3; UFBP1
UniProt ID: (Human) Q96HY6
Entrez Gene ID: (Human) 65992
regulation of intracellular estrogen receptor signaling pathway
response to endoplasmic reticulum stress
positive regulation of NF-kappaB transcription factor activity
positive regulation of proteasomal protein catabolic process
positive regulation of I-kappaB phosphorylation
protein K69-linked ufmylation
