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Proteintech
DUSP16 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
14237-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DUSP16 Fusion Protein Ag5479 (313-662 aa encoded by BC042101)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.33 mg/mL
规格
49.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LLHLEKPNE PVPAVSEGGQ KSETPLSPPC ADSATSEAAG QRPVHPASVP SVQPSLLEDS PLVQALSGLH LSADRLEDSN KLKRSFSLDI KSVSYSASMA ASLHGFSSSE DALEYYKPST TLDGTNKLCQ FSPVQELSEQ TPETSPDKEE ASIPKKLQTA RPSDSQSKRL HSVRTSSSGT AQRSLLSPLH RSGSVEDNYH TSFLFGLSTS QQHLTKSAGL GLKGWHSDIL APQTSTPSLT SSWYFATESS HFYSASAIYG GSASYSAYSC SQLPTCGDQV YSVRRRQKPS DRADSRRSWH EESPFEKQFK RRSCQMEFGE SIMSENRSRE ELGKVGSQSS FSGSMEIIEV S (313-662 aa encoded by BC042101)
靶标信息
Dual-specificity phosphatases constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP16 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK proteins ERK, JNK, and p38 with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25-like domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: MAP kinase phosphatase 7; MAP kinase phosphatase-7; map kinase phosphatase-M; MAPK phosphatase-7; MGC129701; MGC129702; mitogen-activated protein kinase phosphatase 7; MKP-M A1 isoform; protein phosphatase; MKP-M A2 isoform; protein phosphatase; MKP-M B1 isoform; protein phosphatase; MKP-M B2 isoform; protein phosphatase; unnamed protein product
基因别名: 3830417M17Rik; D6Ertd213e; MKP-7; MKP7; Mkpm
UniProt ID: (Human) Q9BY84
Entrez Gene ID: (Human) 80824, (Mouse) 70686, (Rat) 297682
phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity
protein tyrosine phosphatase activity
protein binding
protein tyrosine/threonine phosphatase activity
JUN kinase binding
phosphatase activity
MAP kinase tyrosine/serine/threonine phosphatase activity
MAP kinase tyrosine phosphatase activity
mitogen-activated protein kinase p38 binding
mitogen-activated protein kinase binding
protein carrier chaperone
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