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Recommended positive controls: HL-60.
Predicted reactivity: Mouse (93%), Rat (93%), Rhesus Monkey (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: EPB6; EphB6v; Epherin B6; Epherin receptor B6; Ephrin type-B receptor 6; HEP; human kinase-defective Eph-family receptor protein; MGC129910; MGC129911; Tyrosine-protein kinase-defective receptor EPH-6
基因别名: EPHB6; HEP
UniProt ID: (Human) O15197
Entrez Gene ID: (Human) 2051
分子生物学功能: transmembrane signal receptor