Immunogen sequence: LLLEHLKHKH SRVREEVVNI CICSLLTYPS EDFDLPKLSF DLAPALVDSK RRVRQAALEA FAVLASSMGS GKTSILFKAV DTVELQDNGD GVMNAVQ
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 96%.
Required for normal structure and function of primary cilia. Plays a role in the organization of axoneme microtubule bundles in primary cilia. Interacts with microtubules and promotes microtubule polymerization via its HEAT repeat domains, especially those in TOG region 2 and 4.