Sequence homology: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 79%
FKBP2 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds.
蛋白别名: 13 kDa FK506-binding protein; 13 kDa FKBP; FK506 binding protein 2, 13kDa; FK506-binding protein 2; FK506-binding protein 2 (13kD); FKBP-2; Immunophilin FKBP13; Peptidyl-prolyl cis-trans isomerase FKBP2; PPIase FKBP2; proline isomerase; rapamycin-binding protein; Rotamase
基因别名: FKBP-13; FKBP13; FKBP2; PPIase
UniProt ID: (Human) P26885
Entrez Gene ID: (Human) 2286