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Proteintech
GALNT4 Polyclonal Antibody
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产品信息
12897-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GALNT4 Fusion Protein Ag3590 (230-578 aa encoded by BC036390)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: CECNSGWLE PLLERIGRDE TAVVCPVIDT IDWNTFEFYM QIGEPMIGGF DWRLTFQWHS VPKQERDRRI SRIDPIRSPT MAGGLFAVSK KYFQYLGTYD TGMEVWGGEN LELSFRVWQC GGKLEIHPCS HVGHVFPKRA PYARPNFLQN TARAAEVWMD EYKEHFYNRN PPARKEAYGD ISERKLLRER LRCKSFDWYL KNVFPNLHVP EDRPGWHGAI RSRGISSECL DYNSPDNNPT GANLSLFGCH GQGGNQFFEY TSNKEIRFNS VTELCAEVPE QKNYVGMQNC PKDGFPVPAN IIWHFKEDGT IFHPHSGLCL SAYRTPEGRP DVQMRTCDAL DKNQIWSFEK (230-578 aa encoded by BC036390)
靶标信息
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: GalNAc-T4; Polypeptide GalNAc transferase 4; polypeptide GalNAc transferase-T4; Polypeptide N-acetylgalactosaminyltransferase 4; pp-GaNTase 4; ppGaNTase-T4; Protein-UDP acetylgalactosaminyltransferase 4; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
基因别名: AV011803; GALNAC-T4; GALNACT4; GALNT4
UniProt ID: (Human) Q8N4A0, (Mouse) O08832
Entrez Gene ID: (Human) 8693, (Rat) 500826, (Mouse) 14426
